The primary purpose of this Thesis is to determine the efficacy, safety, and feasibility of ginger in clinical practice through a systematic program of literature reviews, and clinical, survey, and laboratory studies that account for the limitations of the extant literature, and current gaps in the knowledge. In summary, the results of this thesis demonstrate that ginger supplementation is generally safe and feasible, and has several viable mechanisms of action related to CINV. While no reduction in the severity or prevalence of chemotherapy-induced nausea and vomiting (CINV) were reported in our trial, ginger supplementation could be an effective and well-tolerated adjuvant intervention to enhance CINV-related QoL and reduce fatigue. Currently, healthcare professionals are interested in dietary supplements; however, further professional training in this area would improve the integration of dietary supplements into standard clinical practice. Future studies that explore the efficacy and the safety-profile of ginger are warranted in larger clinical trials.
Year Manuscript Completed
Chemical and Pharmacologic Phenomena | Organic Chemicals | Therapeutics
Nausea; Chemotherapy; Ginger; Therapeutic use.
Primary Language of Manuscript
Recommended CitationWolfgang Marx (January 2016) Standardized ginger (Zingiber officinale) extract as a treatment for chemotherapy-induced nausea and vomiting: efficacy, safety and feasibility., PhD, ePublications@bond, Faculty of Health Sciences and Medicine.
01Front.pdf (660 kB)