Fixed-dose combination therapy for hypertension: When should this approach be used?
Date of this Version
Several studies have demonstrated that most patients with hypertension will require two or more anti-hypertensive agents to control their blood pressure.1,2 Blood pressure targets of less than 140/90mmHg for patients with uncomplicated hypertension and less than 130/80mmHg for patients with diabetes or renal dysfunction are now recommended. As a result, fixed-dose combinations of two or even three anti-hypertensive drugs have become widely used.
This document has been peer reviewed.