Date of this Version


Document Type

Journal Article

Publication Details

Published Version.

Bastian, H., Glasziou, P. & Chalmers, I. (2010). Seventy-five trials and eleven systematic reviews a day: How will we ever keep up? PLoS Medicine, 7(9), e1000326.

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2010 HERDC submission. FoR Code: 111717, 110399

2010 Bastian et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Thirty years ago, and a quarter of a century after randomised trials had become widely accepted, Archie Cochrane reproached the medical profession for not having managed to organise a ‘‘critical summary, by speciality or subspeciality, adapted periodically, of all relevant randomised controlled trials’’. Thirty years after Cochrane’s reproach we feel it is timely to consider the extent to which health professionals, the public and policymakers could now use ‘‘critical summaries’’ of trials for their decision-making.



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