Date of this Version

2-1-2014

Document Type

Journal Article

Publication Details

Published Version

Farmer, A.J,. , Stevens, R, Hirst J., Lung T., Oke, J., Clarke, P., Neil, A., Glasziou, P., Dunger, D., Colhourn, H., Pugh, C., Wong, G., Perera, R., & Shine, B. (2014). Optimal strategies for identifying kidney disease in diabetes: properties of screening tests, progression of renal dysfunction and impact of treatment – systematic review and modelling of progression and cost-effectiveness. Health Technol Assessment, 18(14).

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© Copyright, Queen's Printer and Controller of HMSO, 2014

2014 HERDC Submission

ISSN

1366-5278

Abstract

These results support current UK guidance, which recommends annual screening with ACR to identify early kidney disease in patients with diabetes, despite a high false-positive rate leading to, at worst, unnecessary or, at best, early therapeutic intervention. For type 1 diabetes, screening costs for annual compared with 2-yearly screening are well within the bounds of accepted cost-effectiveness. Annual screening is even more cost-effective in type 2 diabetes than in type 1 diabetes. Identification of alternative markers for developing diabetic nephropathy may improve targeting of treatment for those at high risk.

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This document has been peer reviewed.

 

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