Is it feasible for patients to estimate their own 24 hour urine volume?
Date of this Version
Letter to the Editor
Twenty-four hour urine collections are considered to be the 'gold standard' for many assays including urinary albumin, catecholamines, and for the evaluation of proteinuria.1 4 This was advocated as a 24 h urine collection overcame the diumal variation in the various analy tes measured.5 Yet, although the volume of urine produced in the period of 24 h needs to be known to determine the excretion rate of a given analyte, the laboratories only need approximately 10 mL of urine to com plete the assays.6 Previous authors have examined the difficulty in the collection of 24 h urine samples; however, none of these authors ha ve studied the possibility of estimation of urine volume at home.5 7 8 This study examined the feasibility of the measurement of urine volume in the patient's home by comparing self-assessed urine volume with laboratory assessed urine volume. The study included two parts: a preliminary survey and the actual experiment.
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