Date of this Version

4-3-2013

Document Type

Journal Article

Publication Details

Citation only

Bell, K. J. L., Hayen, A., Irwig, L., Takahashi, O., Ohde, S., & Glasziou, P. (2013). When to remeasure cardiovascular risk in untreated people at low and intermediate risk: Observational study. BMJ (Online), 346(7906).

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© Copyright, The Authors, 2013

This work is Licensed a Creative Commons 3.0 License

2013 HERDC submission. FoR Code: 111717: 110399

ISSN

1756-1833

Abstract

Objective: To estimate the probability of becoming high risk for cardiovascular disease among people at low and intermediate risk and not being treated for high blood pressure or lipid levels. Design: Observational study. Setting: General communities in Japan and the United States. Participants: 13 757 participants of the Tokyo health check-up study and 3855 of the Framingham studies aged 30-74 years with complete data on risk equation covariates, not receiving blood pressure or cholesterol lowering treatment, and with an estimated risk of cardiovascular disease20% using the Framingham equation. Results: At baseline most participants had10% probability of crossing the treatment threshold at one year for the 15-

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