Title

Reductions in C-Reactive protein in older adults with type 2 diabetes are related to improvements in body composition following a randomized controlled trial of resistance training

Date of this Version

2-1-2014

Document Type

Journal Article

Publication Details

Citation only

Mavros, Y., Kay, S.,Simpson, K.A., Baker, M., Wang, Y., Zhao, R.R., Meiklejohn, J., Climstein, M., O'Sullivan, A.J. de Vos, N., Baune, B.T., Blair, S.N., Simar, D., Rooney, K., Sing, N., & Fiatarone Sing, M.A. (2013). Reductions in C-Reactive protein in older adults with type 2 diabtees are related to improvements in body composition following a randomized controlled trial of resistance training. Journal Cachexia Sarcopenia Muscle.

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© Copyright, Springer-Verlag Berlin Heidelberg, 2014

ISSN

2190-5991

Abstract

Background Reductions in skeletal muscle mass and increased adiposity are key elements in the aging process and in the pathophysiology of several chronic diseases. Systemic low grade inflammation associated with obesity has been shown to accelerate the age-related decline in skeletal muscle. The aim of this investigation was to determine the effects of 12 months of progressive resistance training (PRT) on systemic inflammation, and whether reductions in systemic inflammation were associated with changes in body composition. We hypothesized that reductions in systemic inflammation following 12 months of PRT in older adults with type 2 diabetes would be associated with reductions in adiposity and increases in skeletal muscle mass.

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This document has been peer reviewed.