Date of this Version


Document Type

Journal Article

Publication Details

Accepted Version.

Jefferson, T., Jones, M., Doshi, P. & Del Mar, C. (2009). Possible harms of oseltamivir—A call for urgent action. The lancet, 374(9698), 1312-1313.

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© Copyright Elsevier Ltd, 2009



Oseltamivir is a successful drug: between July, 2004, and June, 2009, more than 11·5 million new prescriptions were issued in the USA, and nearly all influenza pandemic plans recommend antiviral drugs as a mainstay of containment on a population basis and treatment on an individual basis, with oseltamivir preferred because of ease of administration and storage. Because 75% of the world production of oseltamivir has been used in Japan,¹ this is where to look for any serious harms the drug might cause.

¹ See note in article.

This document has been peer reviewed.