A Microsoft Excel workbook is presented that enables students to explore the Hodgkin-Huxley Model for action potentials in neurons. The model is implemented by a system of four coupled nonlinear ordinary differential equations and requires a numerical solution method. The method used in the workbook is the fourth-order Runge-Kutta method. The workbook provides a user interface to control the simulations by a variety of parameters and to display the model results. All related data is available to allow the addition of charts to the workbook. The workbook is designed to challenge the students’ understanding of the Hodgkin-Huxley Model and to encourage them to create their own simulations that can be checked in a real lab course.
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Geyer, Florian Henning
A Spreadsheet Implementation of the Hodgkin- Huxley Model for Action Potentials in Neurons,
Spreadsheets in Education (eJSiE):
1, Article 1.
Available at: http://epublications.bond.edu.au/ejsie/vol10/iss1/1