Project Title

Targeting metabolic and vascular health with high intensity exercise training in type 2 diabetes

Chief Investigator

Associate Professor Nathan Johnson


Study: Novel Exercise Therapies for Type 2 Diabetes (HIIT Diabetes)

Recent advances in non-invasive imaging techniques have increased the capacity for human research on human pancreas fat (1). A “fatty pancreas” may contribute significantly to the underlying cardiovascular and metabolic dysfunction observed in obesity and related type 2 diabetes (2,3), including beta cell dysfunction (4,5), and diet intervention alone or in combination with bariatric surgery, may reduce pancreas fat and improve pancreatic function (6-9).

This standard operating procedure (SOP) describes the instructions for analysing spectra obtained from the pancreas by localised proton magnetic resonance spectroscopy (1H-MRS) scanning for participants in the Novel Exercise Therapies for Type 2 Diabetes (HIIT Diabetes) research trial. Persons seeking to use spectroscopy analysis


Pancreas fat, Proton magnetic resonance spectroscopy, HIIT Diabetes, Type 2 Diabetes

Document Type

Research Methodology

Lead Organisation

The University of Sydney

Publication Year


Distribution License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

File Format


File Size

2562 KB


Article Location